TSX is as foolproof as bullets get. After driving one on a heavy 1/4 away shot on bull moose at approx 70 yards,I can't imagine a bullet that would have performed better. The 140 gr TSX leave my muzzle at close to 3300 fps, it penterated the entire animal and broke the opposite scapula before coming to rest in the opposite hide, bullet measured .716(284 cal) and weight retention was 93% with a perfect mushroom. The moose of over 1000lbs feel in a heap at the hit and the meat damage to the shoulder was very minimal. I have also used it to harvest 2 bull elk, through the ribs it produced pass through with excellent wound channels and similar 2x the cal exits. One bull actually ran 100 yards the other manged only steps after I took out his heart and bottom lungs at less than 100 yards. On deer I am not sold though my sampling is very small. TSX zipped right through the chest cavity of 3 deer and the wound channel wasn't that impressive. Never lost them but the blood was droplets and required some close inspection to stay on track. Ilike more expansion for the thin skinned animals being a rib mainly shooter but if the pins were my choosen target the TSX would be a super choice for deer sized game IMHO.

BTWI have taken elk and moose with partitions, Failsafes, Accubonds and others they worked. But in the cases of an off angle shot I like the TSX and/orpartitions I know they'll drive to paydirt on larger game!!

As to the result high MV and hitting the neck or any heavy bonewill cause a standard cup and core bullet to expand violently. If your shots are close then either move up in grains size or construction.