Yea, I would have to agree with SwampCollie. The core-lokt are your ticket. I used to live in Seneca(hole in the wall) SC, and there are some big bucks up there...dont be fooled. Never hunted in SC, but Almost hit a huge buck closer to Anderson, so they're out there. I live in GA, and we can only use soft nosed bullets to deer hunt. Your 25-06 is truckin so fast, I would just worry about placement, and let ballistics take over from there.