I tried some of those accelerators in my 30-30. After about 50 yards, they became wildly inaccurate. If the barn was very far away, I couldn't hit the side of it from the inside.

If you are not saving the pelts, just use your normal hunting loads. Even if you are saving pelts, they may be your best bet. If you can hit the vitals without hitting some of the bigger bones, the coyote may be thin enough the bullet won't expand much as it goes through.