ORIGINAL: Alsatian
It seems that Kimber now makes a .25-06 in their Model 8400 rifle that looks pretty sweet. I don't know how well they shoot. I think they cost somewhat more than the bigger name firms's rifles. I think a .25-06 is just about perfect for deer and pronghorn antelope. Dead is dead. I don't know that any other cartridge is going to produce deader deer or deader pronghorn antelope than the .25-06 when constraining your shots to reasonable ranges -- for example 400 yards or less.
The numbers I gave above are at 400 yards. 270 WSM drops -15 and has 1800 or so ft/lbs. About 600 more than .25-06.
That being said I agree. Dead is dead especially with lope. You could do worse than a 25-06 but you could also do better. I'd use it.