RE: How many stick to one load?
Having a proven belief in your load is 100% of accurate shooting. Knowing where the bullet is going to hit and how it preforms lets you have no doubt when the time arrives your bringing meat home or taking home the trophy at the match. I would say the most important thing a shooter or hunter can do is find a perfect load for their rifle. Ignore the upgrades chances are you already found the best. Doesn't hurt to play around in the off season though.
I'll stick with ole reliable. Maybe it should be called the one instead of reliable.