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Magnum Man, what kind of question is this supposed to be? If expense isn't an issue, hell get them both! And as for the reply about living in Alaska, if you can't make do with a 338 a 375 will not help much. The only way a 338 would be inadiquate is if you can't hit with it, and if someone can't shoot a 338 then a 375 is out of the question.
Who said anything about "living in Alaska?" I also believe that the title with "or" in it makes it an either or.