When I fired 300 grain bullets in my .338, I really could not tell much difference in recoil between that and a Remington 375 H&H. But the 338 will shoot flatter and longer with the 225 grainers. The 375 is getting to a different piece... alot more frontal area. Bigger hole. I have a clue you won't be using this much in Arkansas, so I would let the critter and distance be my guide.