RE: How many stick to one load?
It took me so long to find my current load that I doubt I'd have the patience to go much further!
I've got the accuracy I like, but unfortunately I can't judge the on-game performance, since the #*%^$@! elk wouldn't cooperate this year!
My '06 likes Hornady 165gr Interbonds the best, and the only reason I could see switching from that is if they don't drop the bulls very well when I get to that point.