Wouldn't have to think twice. Dead deer. I shoot long range all the time and know my gun well. I have personally taken over a dozendeer that were over 400 yds including one last year at 527 yds. Those were all clean kills and to this day, I have never missed or lost a deer with my rifle. My weapon of choice, is a H.S. Precision .270 WSM topped with a 5X22X56 Nightforce. The bullets are handloaded 130 grain Nosler Ballistic tips. Would I suggest that Joe Blow pick up grandpa's trusty ol' Winchester and fire away. Certainly not. But with good equipment, a good rest, and an experienced shooter that knows what his gun is doing at that range, thereis no reason to pass that shot. The military has been using.308s and 30-06sfor decades to shoot people at ranges much further than 400 yds. Hell, they're expected to hit targets consistently at 500 with iron sights. Don't tell me I can't hita deer at that range with a faster, flatter shooting rifle with a 22 power scope on it.