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It depends on what you are planing on shooting if you are going for any of the big 5 i would use .375 H&H like said before you can find this ammo any where. if you are hunting smaller planes game i would take your deer rifle i have seen every thing from a 75 lb spring buck to 1500lb eland taken with a 7MM so you dont have to have any huge calibers. Take a gun that you can shoot accuratly thats most important.