I assume you are after deer with this rifle since this is a deerhunting board. My particular load groups at 0's at 25 and 225. Its about 1.5 inches high at 100 yds. Since this is a load I know and have used in this rifle for years with the load it made it easier when I put a larger scope on it this year.
Simply put, I started at 25 yards to get it centered. Then shot the 75, 150, 225's. Saved ammo.
Oh and I like target 2 on this link. I print these down and use them. much easier to see those 1 inch blocks even through the 4 power.
http://<a href="http://www.remington...argets.htm</a>
"Size isn't important, but it HELPS!!!"