Out west here, you may be hunting in what WE call a remote area. Like around Hulett, or Ten Sleep, or Centennialand you discover you left your ammo on the kitchen table!
(Hasn't happened to me, but I know a guy . . .)
It is then and there that you are glad you chose a 30-06, or 7mm Mag, or even the 30-30 because that might be the only ammo the local "sporting goods store" carries. For me at least, that is a major consideration.
No the balistics don't match up to some of the more modern lazer beam flat rounds of today, but the .06 is powerfull enough for any North American big game and still comparitivly easy on the shoulder. Still a huge favorite out west where what you shoot is almost as important as where you shoot. (Don't show up with too little gun!)