Shoot LOTS with the .22 get her to like shooting again, then shoot just enough to make sure she knows how to aim the .410. Then explain to her that she will NOT feel the recoil or hear it when she is shooting at a deer.

My son tried to pattern his shotgun for turkey season, took one shot and was reduced to tears, afraid to shoot. I finished the patterning and we went turkey hunting. He never felt the shot and routinely shoots 3 inch mags out of it at duck and deer.