I use the tsx myself and it has been very impressive both with it's accuracy and it's performance on game.The 140grtsx is a good choice for deer or even elk and moose.As for a powder charge,I don't have your rifle,so I can't tell you what charge will work best in your rifle or even what charge will be safe in your rifle.In the rifle that I loaded the 140gr tsx for,66gr was very safe and produced good velocity,but as I said,this was not your rifle.I would start at around 62gr of r-22 and work up from therewatching for pressure signs.