id let yourself be the judge of that. every bow shoots a little diffrent. slower bows will have a bigger pin gap..or use more pins etc.

the main thing is to think about how far YOU feel comfortable. then set pins accordingly. some guys use 1 pin set for 25yds or so. if its closer aim a tad low..farther aim a tad high. some guys use as many pins as they can. this is only my first year but my shooting at 35yds is pretty dang good(not trying to brag..i practiced my butt off this passed month) i can shoot out to 40yds in my backyard, and practice out to 40yds. i decided to set my pins at 15,25, and 35yds. i have 2 more pins not in use as of now. by next year ill have 45 and 55 set. will i ever shot that far for hunting? no..dont plan to. but when your shooting that far 25 and 35yds will seem like its 10yds. you get good groups at 50yds your going to have GREAT groups at normal ranges. another thing it would be nice to have those pins set "incase of an emergency"..take my buddy for instance. hit a buck but his arrow hit the ole "invisible" branch..he seen the arrow in the gut..the buck ran to 40yds or so..stopped..looked at the arrow..bite it and pulled it it out or bit through it..he swears by that. he didnt shoot again because he never shot that far and didnt even know where to start. im a situation like that i would definently try to make the shot. under normal hunting i dont plan to shoot passed 35yds. thats my comfort zone. but i wont do it if its not 100% clear..the deer is calm as well as the wind. its all upto you and your shooting and comfort..