100 yards is what a majority of us sight-in at. Because muzzleloaders can be so be so accuracy-diverse out-of-the-box, I'll hang two large targets side-by-sideat 50 yards to start -- then aim for the center of these two targets... that being the right edge of the one on the left .... left edge of the one on the right. If I'm not on paper to start with such wide target paper toaim at, it usually means my elevation sights are way-off. Then I'll fire at the high side center to correct it -- if that don't get me on paper, I'll shoot at the low edge.

One of them usually gets me started & on my way. That way I avoid the 25 yard range where sometimes a group of pistol shooters,adolescents and children exist. I sight-in usually at 3" high there at the 50 -- then move to the 100 yard range.