Nobody likes the 270 more than I do but the 280 is just a tad more gun in most departments. You can get heavier bullets in the 284 caliber which is what the 280 is. The 30-06, 280 and 270 use the same basic case and are all suitable for the same kind of hunting. All three have bullets with plenty of Sectional Density to hunt North America. The 280 may be the most versitile of the three. However I could live with any one of them if I had to. 280 Ammo does is not found everywhere, that may be its weak point but if you reload, you have it made.