i would suggest staying with a 50 cal. The reason is thats how the world is set up. You are out some where on a hunt and god forbid you loose your bullets and have to go to Luks hardwear store the chances are he will have 50 Cal not necessarly any others. 50 as seen by the pole is the most populat cal. and you can easly get anything you need in that cal a lot of the other cals you may have to order which takes time. my 2 cents