I have had a .222 Rem, 22-250 and a .223. At this point I have settled in with the .223 as I don't have to shoot over 200 yards, and I prefer the lower report. I sold off the 22-250. But if I was out west in the flats, I could see the 250 or the Swift. As far as barrel wear goes, well, heh heh, I shot the barrel out of my old 222 Rem. Fired it that much. Mainly used Hornady SX.