I have discovered that different brands do indeed shoot different. To what degree is the question. And this might not hold true in your rifle for instance. All you can do is shoot a few different brands and see which one does the best for you. I would suggest trying some Hornady, Speer, and Buffalo Bullet Ball. Actually the Speer shoot the best in most of my rifles. Not much better mind you, but group size and consistency, the Speer out do the others. But I would sure hate to live on the difference.