What game are you going to hunt and what will your shot distances be?For deer sized gameonly, the 25-06 is a great choice.It shoots as flat or flatter than a 270win with less recoil,and has plenty of power for any deer.If elk or moose are on the menu,the 280rem or 7mmremmag are great choices.For short to medium distances,the 7mm-08 is a good choice.