The 290 gr in Barnes TMZs is actually a little faster at long range (because of a higher BC) than there 250 gr--- 290 at 200 yds is1458 fpsand the 250 gr at 200 yds is 1435 fps. The energy is greater yet, 1143 ft/lbsfor the 250 and 1368 ft/lbs for the 290. If the heaver recoil from the heavier bullet doesn't bother you, and they both shoot with the same accuracy, the 290 is superior. For deer you may not need the extra energy down range but it can't hurt. Buy the way these are Barnes balistics, not my own personal readings. The 250s seem to shoot slightly more accurately in my Omega, but only slightly.