ORIGINAL: RedAllison
After two days of playing I reached the conclusion that the 204 has nothing on the 22/250 and obviously there is alot more ammo choices (including some deer rounds like the 55grn Trophy Bonded from Federal Prem) available in the 22/250. I
I have shot/owned both. I love both cartridges. If I was forced to pick one I would choose the 204. I love the little bugger. I don't care what anyone tells you the 250 is nothing more than a varmint cartridge. Under no circumstances would I consider it a deer or antelope rifle.
Any round and I mean any round gets sick after 500 yards. Its a whole other ball game out past 500.
I can tell you that the 204 will kill any coyote you want to shoot out to 400 yds, if you can hit him that far.