http://www.handloads.com/calc/bal.htm
according to a ballistic calculator that will figure the BC for you when it is an unknown variable, it says that sighted in dead on at 50 yards produces a -4.87 inch drop at 100 yards. All I can tell you from shooting R.E.A.L. conicals out of my .54 caliber Renegade. I use the 300 grain ones with my own lube and a wad under them. They are sighted in for 50 yards and when we were shooting one afternoon at clay birds set up at all distances, I kept shooting about three inches low at theones far out there. I would have to aim over the birds to hit them. This time the calculator might be right. Those big conicals drop pretty fast.