I wasnt saying a .22-250 is great for deer but in the hands of an experianced shooter it can be a good cal. Id feel more than confident of getting the job done if i had only a .22-250. I agree there are better cals. out there. I disagree fully that the min. should be .25 because a .243 is a great deer caliber. And a great caliber for kids or beginners. There are alot of great premium bullets out there for the .243 that will give great penetration and give you a margin for error if the need did arise due to poor placement. Barnes makes some great bullets for smaller calibers to get the penetration job done.