I have owned this Ruger M77 (25.06) for 24 years now.

Over the years it has taken numerous deer some of which were quite large. I have also shot a few bear and one small moose with it. Lots of groundhogs and a few coyotes have also tasted its lead.
For game from deer size & smaller it is an excellent choice.
For larger game you have to be very particular in the choice your shots. Not the best choice but will work if you keep the shots to a shorter range & place the bullet in the proper place.

Best Wishes