I consider the 25-06 a good choice for large deer, I just consider the 270 a bit better. I consider the 270 a fair elk and moose rifle but consider the 30-06 a bit better. I shoot almost all 100 grain bullets in the 25-06 because try as I have, I have not seen the 120 grain bullets be any more effective than the 100 grains for deer. I would use a good 130-140 grain for the 270 95 percent of the time. I may give the 150's a try in the 270 WSM.

Others see flaws in my thinking though. Most of those people are my wife.