How can you ask a question like that???[:@]Thats a next to impossible question. It varies but I would say the 6.5x55 Mauser is at or near the top of my list. followed closely by the 45 ACP Ruger and the Taurus Model 65 357 Mag. I hate to think of how many that leaves out.The old Mauser always hits the target and never hurts the shoulder. What not to love. Also, the critters die very fast.