I have seen MANY carbons that were not straight, right out of the box.
Will you notice it? Depends on how well you shoot and what you are doing. For 20- 30 yards with field tips, maybe not unless you have excellent form. Now put a fixed blade head on it and it will be quite noticable if you try to tune or group them. Also the amount of fletch and FOC you have may make a difference as well.
The biggest thing is if the arrow is not straight, especially a carbon then chances are the spine is not correct either.