I have 3 gun recomendations:

1) The Sig 229 would be a good choice for several reasons. One you can get it in .40 S&W with a 12 round capacity. You mentioned not having an external safety on the Glock. The Sig doesn't either, it has a decocker lever that allows you to carry with one in the tube. The trigger is a double action/single action trigger, so when you go to fire, the double action kicks in off the first shot and then automatically goes to single action after the first round is fired.

2) My second suggestion would be a Springfield Armory XD in .45ACP. The gun is awesome! It feels great in the hands and is incredibly light weight. The trigger is very nice and smooth, as well as the slide. It is a striker fired gun like the glock, so there is no hammer to snag. The gun is almost exactly like the glock, except for one difference. It has a safety in the pistol grip, making it much safer for concealed carry. The greatest thing about the XD, is that it holds 14 rounds of .45ACP and is still light!

3) My third choice for a CC pistol would be a 1911. The gun is a classic pistol in .45 ACP with a 7 shot capacity. It is much thinner, which makes it easier to conceal, so it doesn't "print". It is a tad heavier for wearing on your wasteband, but the added weight makes recoil much less felt. There are many different 1911 manufacturers out there, but the one I will be going with will be the Springfield Armory 1911 Mil-Spec in .45 ACP. The gun shoots very accurately and is really comfortable. Last week at the range, I shot 7 shots in under a minute with all the holes touching at 7 yards

Looking back at your post, I didn't really pick any of your choices, sorry about that. Many many people have chosen the three I've recommended including agencies like SWAT, FBI, and others out there. I will carry a 1911 for if, and God forbid when my life is in danger. Good luck in making your decision, and I hope you never NEED it.