I own a Ruger M77 (tang safety) in 25.06.
Weight of pull can be adjusted with out removing the action from the stock. The other two screws cannot but seldom require adjustment.
To adjust the weight of pull use a allen key inserted though the trigger guard. Turning it counterclockwise reduces the weight of pull to as light as two pounds. Be carefull as to light of a setting can be dangerous in hunting situations.

Best Wishes