I have been using CCI benchrest primers in all my rifle calibers and I'm very happy with the groups I've been getting. Well not in my 45-70,I still use CCI200's in it. I'm not sure just how much difference the primers make as far as the brand goes. They all must have similar compisitions in the priming mixture. The biggest difference could be in the quality control, and that's why I use CCI as I've been doing for 30 something years.