You prob wont beat a Glock. There are a ton of different configurations so go and handel a couple of them and see which model best fits you. They have about the best reputation around for automatic handguns. Just make sure your fingers are strong\long enough to work the release on the side. They are made for carry so they dont stick out much to get any extra leverage on them.

The Springfield XDs are pretty nice also. You cant go wrong with most of the big name 1911's also if they fityour hand but a 45 is alot of gun if its you 1st.