One is a long action and other is a short action.

280rem is almost a 7mmremmag, and I know several folks that find accurate reloads that exceeds some accurate rem mag loads. 7mm-08 is one of the most ideal whitetail calibers, but only expect 2700fps for a 140gr bullet. 280 recoils a little more. Thats about it.

Here is what I do in your situation. Take a coin and flip it in the air, heads 7mm-8, tails 280, cause none of the animals will care you shoot.