I own four bows, one of them being a bowtech and it doesn't matter. They state the effeciency falls off, but I didn't notice when I chronoed it at different draw weights using different arrows. After doing the math it still fell within the stated IBO speeds. Anything you do could potentially effect the effeciency of the bow, like shooting it at a lower poundage, or using a shorter draw length, or having the cam/s out of time. However my Mighty Might with the single cam is set at 26 inches, 53 lbs and the draw stop is slighty off to give me a bit of a valley and a bit more let off. It is still pretty effecient. Same with my darton with the CPS cams.

On a really old bow it may effect if the bow has more vibration or noise, but none of the bows I have seen made in the last 5 years or so should be effected by this, even older ones for that matter. It should not effect accuracy at all providing you didn't throw your nock point off doing it or severely changed your arrow spine. However anytime you change anything on your bow it may require re-tuning.

Paul