RE: 22-250 vs 243 for coyote?
I'm going with the .243 as well. I will put a muzzlebreak on it so I can shoot 200 - 300 times a day and not need surgery.(lol)
I will want to experiment with 75 - 100 gr bullets because I will want one that disintih=grates and does not cause an exit wound.Moneyfor yote hides around here.
~AND~ . . . .243 is legal for deer and Antelopes here.