I've shot 2 deer with a roundball from a Charles Daly Hawken. 90 gr Pyrodex. The first was the standard double lung hit with pass thru, good blood trail, etc. The 2nd was more memorable: I shot her in the front shoulder, quartering to me at about 40 yards. I found hair where she was standing, but no blood or blood trail, but snow made tracking easy, where I found her about 100 yards away. I found the roundball had broken into at least 4 pieces, but they made it into the boiler room, one piece was lodged in the heart.
IM jaybe