I was using the Hornady's out of my .243 exclusively. I dropped a 200 pound boar at 220 yds with it. I mean dropped it, I could hear his head hit the ground. Complete pass through on the neck, same with deer, I put some big 'ol holes through deer with them also.
Past two years I have been using federals with the sierra game kings, not much difference if any, cheaper and easier to find.
but to answer your question, Hornady makes fine ammo. I would highly reccomend them.