.40S&W is my favorite and has been for a couple years now.
I use 155 grain Hydras when I carry. At all ranges under 50 yards, its going faster and has more energy than the 165 and 180 grains. On the opposite side, you can argue that the heavier bullet will be harder to deflect and might get thru thicker garments better, but Ive shot telephone books, milk jugs, you name it, with all 3 weights, and I like what the 155 does. Not to mention my Sig loves them.
I have recently fallen inlove 165 grain Golden Sabers from Remington. Actually, after I shoot the rest of these Hydras, Im going to Sabers full time. Slightly more potent than Federals Hydras, and from hands on experience from people who have used both, the Sabers are more reliable when it comes to penetration and proper mushrooming.
I'll run more tests on them when I get a few boxes