From all I have read on the Barnes Expanders their ability to produce excellent wound channels and achieve excellent penetration even on thick skinned or larger animals is excellent. I have personally never gotten to shoot an animal with them as of yet. I do get some outstanding accuracy with them in my Knight Rifles. I also switched to the Barnes XPB handgun bullets. They are almost identical to the Barnes Expander in design except they have a crimp ring for loading into cartridge casings. The other nice thing about them is they are much more buyer friendly then the Expanders.

I shoot 100 grains of Goex 3f and a 250 grain Barnes Expander in my Knight Wolverine with excellent results. I have never shot them over 100 yards on targets yet so I can not comment on long range abilities. I normally shoot under a 2" group with them at 100 yards.