Well my 1 in 38 twist System One likes bullets from 180 to 260 gr. in 44 or 45 cal. it shoots 45 cal 230 gr. best with 150APP. hitting the back edge of the shoulder just at the top of the heart with it drops them on the spot over 50 percent of the time.
My new Omega which I am just getting going likes the Shock Wave 50/40 200gr. with 150 APP tears a ragged hole @ at 100yd. the 250 gr. Shock wave will shoot a nice 1 inch group but it only doesit with 110 gr. which is a bit light for me.The 300gr XTP shot nice groups with 100 grAPP which is a nice target load.250XTP 245PB and 250 Sabor Toothall shoot in the 2 to 3 inch @100yd.
Since I use twist both faster and slower than yours I though you might find this interesting maybe get some ideas. Be safe & enjoy. Lee