I guess I could only vote once.My primary rifle of choice is 30-06 but I just got a 6mm Rem this year and its deadly as well. I've taken several with a good 'ole 30-30 as well and 44 mag lever action and Ruger Super Blackhawk also Ruger Vaquero in 45LC. I also have a 308 M1 Garand that I won that I'd like to take a nice buck with. What about 25-06? I'm sure there'd be a few votes for that.