I don't reload YET. Been thinking about it and probably will start soon.

I have found that I use different wieght bullets in my rifles based on the rifles performance and the confidense I have in the bullet load.

I rarely use my Remington 742 in places where I have to shoot over 150 yards. I have found that this rifle in the best brush gun I have ever owned. I shoot standard factory Remington 180gr rounded soft core lok's. This has been the best for me and I have only lost one deer in 34 years of hunting when using this rifle. The deer I could not find was because of a poorly placed chest shot on my part that actually went between the shoulder and the chest. We found the deer the next day but the meat was ruined because it was fairly warm. The 180 gr load has tremendous knock down power in this rifle.

On the other hand the .280 I owned I used 140gr remington pointed soft cor lok's and had very good performance with the bullet out to 400 yards with my best shot killing a deer at 375 yards. Once again shooter performance has a lot to do with it but the deer dropped dead in it tracks.

My Remington 700 BDL .30-06 I use 165gr Point Soft Cor Lok's and have had great performance out to 250 yards. No lost animals with very few running more 20 yards and a large majority dropping in their tracks.

The only time I have had poor performance was with a 30-30 using 150gr Hornady silver tips and that was back in the 70's. I got literally no bullet expansion. I shot a deer 6 times before it went down. And then I had to put one in the brain bucket before it was dead. I started out with a chest shot and then the deer ran by me and I just kept jack the shells in it. I dug out 6 bullets that expanded to a little over the original bullet size. Could've been cheap ammo I dunno.

I guess what it comes down to is what works for you, what confidence you have in the bullet weight, and your shooting skills.