RE: 204 or 22-250
Bigcountry - I have built a bunch of .204's and 20 Tacticals for varmint hunters - many of which already own .22-250's or 220 Swifts. They seem to univerally like them for prairie dogs. And the barrel life is pretty good. One of the first .204's I built has come back to be rebarreled already - he got an estimated 4,000 rounds out of the Douglas XXX CM barrel.
Downside is that, even though the ballistics look pretty goodon paper - they don't put a big tough coyoteon the groundat long range like the big 22 CF's do. Great calling guns - for shots out to 300 yards or so. And minimal pelt damage.
PS - so far the 39 Sierra seems to get the nod as the best coyote/bobcat bullet.