My go-to coyote gun used to be a Remington 700 ADL in 223. I had 2 bad experiences with it while calling coyotes, and I started to lean towards a bigger gun. This was mainly due to a bad choice in ammo selection. I was loading Nosler 40gr BTs to max load, and I shot 2 coyotes right behind the shoulder that I end up having to blood trail almost a half mile before catching up to them and finishing them off. The problem was the bullet was hitting the shoulder blade and blowing up, causing a massive flesh wound. I did, however, kill many coyotes with the 50gr Hornaday VMax and Speer 52gr TNT HP.

The 223 will make a dandy coyote gun, but your range will be a little more limited. Now I use a 243, and I don't know if I will ever switch back to a 223. I have been eyeballing a few 22-250s tho.....