My fastest kills have been with high velocity cartridges and rapid expanding bullets like the nolser ballistic tip.I dropped several large bodied deer on the spot by using the 100gr ballistic point out of my 257wby and many morewith the 140gr ballistic tip out of my 7mmstws.I use lung shots and not one deer has travelled 50 yards with most dropping on the spot or within a few yards.I have done the same thing with elk and moose using my 300ultramags.