It would be advantageous to use varmint bullets for varmints, and big game bullets for big game. It is not humane to use varmint bullets on big game due to their lack of integrety. If you don't handload I suggest you look into it; I don't think Weatherby loads any varmint rounds.Iguess you could use Weatherby 115 gr. Nosler Ballistic Tips for both. For hogs I would go with a Weatherby 115 gr. Barnes-X, or 120 gr. Nosler Partition.Good luck.