If you hit big bones, you will want the Partition or the TSX. If you are hunting out of tree stand and have the opportunity to wait for a good angle, however, the lungs are a pretty good size target and the 85 Sierra will usually put them on the ground quickly. Partitions and TSX bullets, in the .243/6MM, don't generally kill very quickly on broadside rib shots. Fairly small wound channel. Great for shoulders, though, and can even penetrate a deer end-for-end if necessary.