RE: 460 S&W
My reasoning with the 460 was because of the max point blank range. Sight it in at 200 yards, and hold dead on out to 250. And they are capable of minute of angle accuracy. You can also shoot 454 casull and 45LC out of it. But I really am starting to think against it. It is tough getting one, and they are expensive. For no more than I will be shooting it.