I personally shoot a .223 and shoot out to 300yrds. I have a lot of guys bash me for using a 223 and they all say the 22-250 is so better but i change there minds when i kill them at 300 yrds and they dont or at the range when i shoot better groups at 300 yrds then they do at 200 so imo the 223 is better and cheaper to shoot with all the surplus ammo out there.